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CH
Chidiebube Ugwu, MD, MPH

Associated researcher

Chidiebube Ugwu, MD, MPH

Clinician Scientist

Jefferson Einstein Philadelphia Hospital

Philadelphia, PA, USA

Studying why outcomes in blood cancers differ by race and ancestry: TP53 co-mutation networks in multiple myeloma (AACR Project GENIE; oral abstract, AACR 2026), ancestry-resolved mutation patterns in myelodysplastic neoplasm, and real-world evidence on tyrosine kinase inhibitor switching in chronic myeloid leukemia.

What they study

Whether differences in blood-cancer outcomes by race and ancestry are driven by the architecture of co-occurring mutations, and whether risk classifiers trained mainly in European-ancestry cohorts perform equally across ancestry groups.

How they study it

  • AACR Project GENIE, MSK-IMPACT, TARGET, cBioPortal, TriNetX
  • Co-occurrence and network analysis
  • Propensity score matching, Cox regression, Kaplan–Meier